The RPE65 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to RPE65. This antibody recognizes Human, and Rat antigen. The RPE65 Antibody has been validated for the following applications: ELISA, Immunofluorescence, and Western Blot.
Description
Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association